Vitamin D3 + K2: Basic Supply for the Whole Family
Good for bones, muscles and immune system*
✓ 800 IU (20 µg) Vitamin D3 + 20 µg Vitamin K2 (all-trans MK7) per drop
✓ Made in Germany with Vitamin D3 + K2 from Europe, pharmacopoeia quality
✓ Optimally bioavailable and stable thanks to natural Vitamin E
✓ Expertise + experience: first Vitamin D3K2 oil in German pharmacies (since 2015)
✓ Excellent price-dose ratio: 640 drops, vegetarian
20 ml (640 drops)
Why do we need the combination of Vitamin D3 and K2?
Vitamin D is essential for the maintenance of bones and teeth, the function of muscles and the immune system, and plays a role in cell division. For the maintenance of normal bones, it works closely with Vitamin K: Vitamin D3 stimulates the production of osteocalcin, which is activated by Vitamin K2 to efficiently incorporate calcium into the bones.
Vitamin K2 is barely absorbed through diet. Dr. Jacob’s Vitamin D3K2 Oil contains long-chain Vitamin K2 (menaquinone-7) with high bioavailability and stability. It remains in the body for up to three days, approximately 50 times longer than Vitamin K1.
Only 12% have good Vitamin D3 levels, in winter it is less than 5%
Diet contributes little to Vitamin D supply; essential is UVB sunlight for endogenous synthesis in the skin. A deficiency is particularly common in winter, but even in summer, factors such as sun protection or a dark skin type can inhibit Vitamin D synthesis. Studies show that endogenous production is often insufficient even in summer:
Only 12% of the German population achieve the Vitamin D level of over 75 nmol/l (1,2) recommended by leading scientists on an annual average, and less than 5% in winter. Only 38% of Germans achieve the lower limit of at least 50 nmol/l set by the German Nutrition Society (DGE) year-round. (3)
Experts also disagree on the correct intake recommendation. In fact, this depends on many factors: baseline value, age, weight, sun exposure, skin color, etc. The DGE recommends a serum level of at least 50 nmol/l and 800 IU (20 µg) of Vitamin D daily (from the age of 2, in case of insufficient endogenous synthesis).
The renowned American Geriatrics Society recommends 4000 IU (100 µg) of Vitamin D daily (from all sources) for all persons aged 70 and above, to maintain a good serum level of at least 75 nmol/l. This corresponds to the daily intake deemed safe (tolerable) by the European Food Safety Authority (EFSA) for persons aged 11 and above.
(1)Holick et al. J Clin Endocrinol Metab (2011) 96(7):1911-30. (2)Bischoff-Ferrari et al. Am J Clin Nutr (2006) 84(1):18-28. (3)Rabenberg et al. BMC Public Health (2015) 15:641; Good Vitamin D level ≥ 75 nmol/l 25(OH)D, according to Holick et al. J Clin Endocrinol Metab (2011) 96(7):1911-30.
Who should pay particular attention to their Vitamin D level?
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Everyone in months with low UV radiation (October to March)
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Persons who spend most of their time indoors or cover their skin
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Users of sunscreens (SPF 10 reduces Vitamin D production by 90%)
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Persons with dark skin type
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Pregnant women, nursing mothers, babies and toddlers
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Women in/after menopause
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Overweight individuals
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Seniors
A Vitamin D blood test (at the doctor, in the pharmacy or a self-test) provides clarity.
Vitamin D3K2 Drops – for Bones and Immune System*
*The vitamins contained in Dr. Jacob’s Vitamin D3K2 Oil contribute to the following normal bodily functions:
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Maintenance of bones – Vitamin D and K
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Maintenance of teeth – Vitamin D
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Maintenance of muscle function – Vitamin D
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Immune system – Vitamin D
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Plays a role in cell division – Vitamin D
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Normal absorption and utilization of calcium – Vitamin D
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Normal blood clotting – Vitamin K
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Reduction of fall risk** – Vitamin D
**In women and men aged 60 and over, falls represent a risk factor for bone fractures. The increased risk of falls in old age may be related to Vitamin D supply. Daily intake of 800 IU (20 μg) of Vitamin D from all sources contributes in people aged 60 and over to the reduction of fall risk, which is associated with muscle weakness and physical instability. Falls are caused by several risk factors. A change in one of these risk factors may, but does not necessarily, show a positive effect.
Proven Quality at a Fair Price
Already in 2015, Dr. Jacob’s was the first manufacturer to introduce a Vitamin D3K2 oil to German pharmacies. To this day, Dr. Jacob’s Vitamin D3K2 Oil is produced in Germany. The vitamins used are of pharmacopoeia quality and come from Europe.
Dr. Jacob’s Vitamin Oils are easy to dose, child-friendly and also ideal for people with swallowing difficulties. One bottle contains 640 drops with 20 μg (800 IU) D3 + 20 μg K2 (all-trans MK-7) per drop.
What is special about Vitamin K2 Menaquinone-7?
Dr. Jacob’s Vitamin Oils provide Vitamin K2 in the form of menaquinone-7 (all-trans MK-7). This form can be particularly well absorbed and utilized by the body compared to Vitamin K1 and other K2 forms. Thanks to its high stability, approximately half of the vitamin is still detectable in the blood after three days, whereas Vitamin K1 has a half-life of only 1.5 h (Schurgers et al., 2007).
The Vitamin K2 menaquinone-7 we use comes from Europe and is particularly pure and effective*. It contains almost 100% of the active, natural form of Vitamin K2, the so-called trans-form.
For comparison: analyses of common Vitamin K2 raw materials from China showed unknown chemical impurities of 88–90%. Lower quality Vitamin K2 contains, in addition to the biologically active trans-form, a high proportion of the biologically inactive cis-form.
Natural Vitamin E and MCT Oil for Optimal Protection and Stability
Vitamins D3 and K2 are very sensitive to oxidation. Dr. Jacob’s Vitamin D3K2 Oil therefore contains natural Vitamin E (tocopherols) as an antioxidant in the optimal dosage. This is crucial, as both too little and too much Vitamin E can accelerate the breakdown of Vitamin D3 and K2. The right amount ensures the vitamin content until the best-before date. Regular analyses confirm the long-term stability of the vitamin content.
Additionally, high-quality MCT oil from coconut oil protects the sensitive vitamin and improves its absorption in the body. Medium-chain triglycerides (MCTs) are more stable than long-chain fatty acids, such as those found in olive oil, and thus offer better protection against oxidation.
Dr. Jacob's Vitamin Oils benefit from the manufacturer's many years of experience – a quality that imitators lack.
Best Interaction: The Ideal Partners of Vitamin D
Not only Vitamin D3 contributes to the maintenance of normal bones, but also Vitamin K2. Both work synergistically and should ideally be taken in combination.
Calcium metabolism is closely linked to magnesium and potassium. Magnesium supports the maintenance of normal bones and the normal function of nerves and muscles. Potassium contributes to the normal function of muscles and the nervous system, as well as to the maintenance of normal blood pressure. According to NVS2, a deficiency in these minerals is common (4).
(4)National Consumption Study 2 (MRI 2008).